Tennessee Over Florida, Clemson over Louisville Among Top 25 Predictions

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In their classic matchup last season which turned into a showdown between Lamar Jackson and Deshaun Watson - the eventual Heisman Trophy victor and runner-up, respectively - the Tigers blew an 18-point lead, rallying for two fourth-quarter touchdowns, stopping the Cardinals a yard short on fourth down with 33 seconds left to hold on for the win.

ABOUT LOUISVILLE (2-0, 1-0): Jackson has accounted for 1,010 yards of total offense in a stellar start to his bid to become the second two-time Heisman Trophy victor. He collected 485 yards of total offense and two touchdowns during the opener against Purdue, then amassed 525 yards and six scores at North Carolina.

When Bryant returned, he led an 88-yard scoring drive that he ended with a three-yard TD run to take the lead for good.

Still, Kelly Bryant, the Tigers' first-year starting quarterback, is going on the road for the first time.

Kelly Bryant is a solid replacement for the departed Deshaun Watson and last week played well against a very good Auburn defense, completing19 of 29 passes for 181 yards and leading the team in rushing with 59 yards on 19 carries. Because the foul happened in the first half, he won't be suspended for any of Clemson's next game. The computer is taking the Tigers to cover the spread, and the over on the point total. While there's only one marquee game this coming weekend, there's a lot to look forward to, and look back on. Whether you like the show or not, you have to admit it's a staple of every Saturday before the games begin to kickoff at noon. He passed for 393 yards with three passing touchdowns and ran for 132 and had three more scores.

Week 3 of the 2017 college football schedule will be back in full force this Saturday, and one game in particular will have a direct effect on the top 25 standings at week's end.

Louisville is led by reigning Heisman victor Lamar Jackson, who has scored eight touchdowns through the first two games of the season.

Approximating those statistics, however, figured to be a chore against Clemson, which features one of the most menacing defensive lines in the country.

No. 16 Virginia Tech (2-0) at East Carolina (0-2), 3:30 p.m. (CBSSN): The Hokie have never found it easy against the Pirates and last year's 54-17 victory snapped a two-game losing streak. From generational talents in Dexter Lawrence and Christian Wilkins to versatile pass rushers in Austin Bryant and Clelin Ferrell, the defensive line is stacked with freak athletes who are capable of impacting the game in a significant way. He also rushed for a pair of touchdowns and threw for another. The Tigers will be on the road this Saturday night squaring off against the Louisville Cardinals.

Can the Louisville supporting cast make enough big plays on both sides of the ball? How you prepare and that's all that determines how you're going to play.

Clemson just dominated Auburn with their defensive front a week ago totaling 11 sacks, meaning this will be the ultimate test for football's version of Houdini. The junior QB has basically been Clemson's entire offense as the Tigers have failed to establish a consistent running attack through two games.

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